NEBL — Nebulette
NEBL belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NEBL's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Arterial EC Identity Endothelial cell development | AFAP1L2, BMP4, CFAP36, FUT8, ITPR2, JAG1, LTBP4, NPTXR +6 more | View in SCUBA |
| Enterocytes | Cortical actin junctions Cytoskeletal | GOLGB1, JAK2, MYO1B, PKP4, STXBP5, TTC39B | View in SCUBA |
About the gene
| Synonyms | bA165O3.1, C10orf113, LASP2, LNEBL |
|---|---|
| Chromosome | 10: 20779973-21293011 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Actin-binding |
Function
Binds to actin and plays an important role in the assembly of the Z-disk. May functionally link sarcomeric actin to the desmin intermediate filaments in the heart muscle sarcomeres. May play a role in the assembly of focal adhesions
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.