TMX2 — Thioredoxin related transmembrane protein 2
TMX2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TMX2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Glycolytic Metabolism Housekeeping | ARL1, ARPC5, ATP5PB, ATRAID, C4orf3, CALM1, CAPZA2, CHMP5 +30 more | View in SCUBA |
About the gene
| Synonyms | PDIA12, TXNDC14 |
|---|---|
| Chromosome | 11: 57712593-57740973 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
Function
Endoplasmic reticulum and mitochondria-associated protein that probably functions as a regulator of cellular redox state and thereby regulates protein post-translational modification, protein folding and mitochondrial activity. Indirectly regulates neuronal proliferation, migration, and organization in the developing brain
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.