ATP5MC3 — ATP synthase membrane subunit c locus 3
ATP5MC3 belongs to a gene co-expression module in 12 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ATP5MC3's module in each cell type
About the gene
| Synonyms | ATP5G3 |
|---|---|
| Chromosome | 2: 175176258-175181710 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters |
| Biological process | Hydrogen ion transport, Ion transport, Transport |
Function
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.