VPREB1 — V-set pre-B cell surrogate light chain 1
VPREB1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
VPREB1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | Pro-B Progenitor Lymphcyte development | ARPP21, CD79A, CD79B, CYGB, DNTT, EBF1, FRMD4A, IL2RA +4 more |
About the gene
| Synonyms | CD179A, VpreB |
|---|---|
| Chromosome | 22: 22244780-22245515 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | CD markers, Predicted intracellular proteins |
Function
Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B- cell differentiation
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.