GULP1/PRDM16 EC genes
Gene co-expression module in Enteroendocrine cells
| Category | Enterochromaffin program |
|---|---|
| Genes | 0 |
| Annotation certainty | 3 of 5 |
| Annotation consistency | 0 of 7 genes have a known function matching the annotation |
Why this annotation
This tightly coherent module is localized 4-5x to EC cells (GULP1, DNAI3, FAM184A, KLHL29, NSUN7, PRDM16), and no atlas cell type expresses these genes more highly, so it is a genuine EC-subset program. It lacks serotonin-pathway genes and has no defined biochemical function, so it is named by its hub genes; it co-varies with the other EC identity modules.
Genes
Most correlated modules
- SV2C/KCNS3 EC program · correlation 0.89
- GREM2/CDH26 EC subset · correlation 0.87
- SYT1/ATP6V1C2 vesicle genes · correlation 0.87
- EC accessory genes · correlation 0.86
- LMX1A/VMAT1 EC identity · correlation 0.84
- Synaptic scaffold/regulators · correlation 0.82
- NAT8L/APOD EC subset · correlation 0.81
- TF-defined EC subtype · correlation 0.81
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.