CADM1/ANK2 adhesion axis
Gene co-expression module in Enteroendocrine cells
| Category | migration & adhesion |
|---|---|
| Genes | 0 |
| Annotation certainty | 3 of 5 |
| Annotation consistency | 5 of 9 genes have a known function matching the annotation |
Why this annotation
Hubs CADM1 (neuropod synaptic adhesion), ANK2, FMN2, NEBL and ADGRV1 define a neuron-like adhesion/cytoskeletal axis that is only mildly enriched in EC and D cells; its tight correlation with «Neuropod Synaptic Machinery» supports a genuine neuropod-related program rather than a purely long-gene capture artifact.
Genes
Most correlated modules
- L-cell Ciliary Genes · correlation 0.84
- EC Calcium-Triggered Exocytosis · correlation 0.84
- D/L-cell lineage signature · correlation 0.82
- FHL1/SCN8A EC state · correlation 0.82
- Posterior HOX code · correlation 0.79
- EC/D presynaptic machinery · correlation 0.79
- CDH22/SPATA17 EC markers · correlation 0.78
- SYT4+ vesicle state · correlation 0.77
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.