Respiratory chain subunits
Gene co-expression module in Enteroendocrine cells
| Category | Mitochondrial & OxPhos |
|---|---|
| Genes | 0 |
| Annotation certainty | 5 of 5 |
| Annotation consistency | 15 of 19 genes have a known function matching the annotation |
Why this annotation
The hubs are nuclear-encoded subunits of complexes I, III and IV and of ATP synthase, forming a tightly coherent OxPhos module. It is spread across subsets, and no other cell type expresses these genes more.
Genes
Most correlated modules
- Biosynthetic housekeeping machinery · correlation 0.94
- Abundant housekeeping transcripts · correlation 0.92
- Ribosome/translation machinery · correlation 0.88
- Chaperonin/MYC growth genes · correlation 0.76
- Progenitor hnRNP program · correlation 0.75
- CDKN1C cycle-exit progenitor · correlation 0.74
- HES6 progenitor commitment · correlation 0.67
- WNT9A/L1TD1 pre-EEC state · correlation 0.66
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.