Intracellular Cargo Transport
Gene co-expression module in Microfold-like cells
| Category | Housekeeping |
|---|---|
| Genes | 0 |
| Annotation certainty | 3 of 5 |
| Annotation consistency | 7 of 10 genes have a known function matching the annotation |
Why this annotation
KIF5B (kinesin-1 motor for vesicle/organelle transport), RAB4A (early endosome recycling), LMAN1 (ER-to-Golgi cargo receptor/ERGIC-53), FNBP1L (formin-binding, actin/endocytosis), and MTPN (actin capping) define an intracellular cargo transport program. ANAPC16 and UBE2R2 add ubiquitin-proteasome regulation of cargo. SBDS (ribosome biogenesis), MOB1A (Hippo), and CCNG1 (cyclin G1) are peripheral. The dominant theme is vesicular/motor-driven intracellular transport, neighboring M92's endosomal trafficking program.
Genes
Most correlated modules
- BMP-ECM Signaling · correlation 0.99
- Endosomal Vesicle Trafficking · correlation 0.99
- Membrane Trafficking · correlation 0.99
- Membrane Remodeling mTOR · correlation 0.99
- Apoptosis Regulation · correlation 0.99
- Organelle Homeostasis · correlation 0.99
- Macrophage Homeostasis · correlation 0.99
- ER Redox Homeostasis · correlation 0.99
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.