Membrane Remodeling mTOR
Gene co-expression module in Microfold-like cells
| Category | Housekeeping |
|---|---|
| Genes | 0 |
| Annotation certainty | 3 of 5 |
| Annotation consistency | 7 of 8 genes have a known function matching the annotation |
Why this annotation
Hub genes PLSCR1 (phospholipid scramblase, membrane phospholipid redistribution during apoptosis/signaling), RHEB (RAS homolog enriched in brain, mTORC1 activator), CMAS (CMP-sialic acid synthetase, glycosylation), RAB14 (endosomal RAB GTPase, vesicle trafficking), VAPA (VAMP-associated protein, ER-membrane contact sites), ANXA5 (annexin V, phosphatidylserine binding/membrane), RPN2 (oligosaccharyltransferase), and CAPN2 (calpain-2 protease) collectively reflect membrane remodeling, vesicle trafficking, and mTOR-linked signaling. The module is a housekeeping membrane biology program with mTOR signaling input.
Genes
Most correlated modules
- Actin & Membrane · correlation 0.99
- Intracellular Cargo Transport · correlation 0.99
- ER Redox Homeostasis · correlation 0.99
- Endosomal Vesicle Trafficking · correlation 0.99
- Apoptosis Regulation · correlation 0.98
- BMP-ECM Signaling · correlation 0.98
- Metabolic Housekeeping · correlation 0.98
- ER Membrane Trafficking · correlation 0.98
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.