Cellular Housekeeping Mixed
Gene co-expression module in Mast cells
| Category | Housekeeping |
|---|---|
| Genes | 0 |
| Annotation certainty | 2 of 5 |
| Annotation consistency | 11 of 19 genes have a known function matching the annotation |
Why this annotation
Hub genes span nuclear pore (POM121), phospholipid transport (ATP11B), translation initiation (EIF4H), transcriptional coactivation (YY1AP1), RNA splicing (LUC7L2), COPII vesicle budding (SEC16A), and mitochondrial complex II (SDHA). All subsets show uniform low-moderate expression with no disease-specific enrichment. This is a mixed housekeeping module covering basic cellular maintenance processes without a dominant single pathway.
Genes
Most correlated modules
- Autophagy Lysosomal Program · correlation 0.92
- General Housekeeping · correlation 0.92
- PI3K-Wnt Signaling · correlation 0.89
- ER Protein Quality Control · correlation 0.89
- Ubiquitin-Chromatin Regulation · correlation 0.88
- RNA & Membrane Housekeeping · correlation 0.88
- Endosomal Trafficking · correlation 0.87
- DNA Damage Response · correlation 0.86
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.