Mitotic Spindle
Gene co-expression module in Mast cells
| Category | Cell cycle |
|---|---|
| Genes | 0 |
| Annotation certainty | 4 of 5 |
| Annotation consistency | 8 of 10 genes have a known function matching the annotation |
Why this annotation
Hub genes NUSAP1 (spindle microtubule organization), CKS1B (CDK1 regulator, G2/M), CENPW (kinetochore assembly), NUF2 (kinetochore-microtubule attachment), NCAPD2 (condensin I, chromosome condensation), HMGB3 (chromatin compaction in mitosis), DTYMK (dTMP kinase, nucleotide metabolism for division) define a mitotic/G2-M program. Topological neighbor to M168 (S-phase), together spanning the full cell cycle in proliferating mast cells.
Genes
Most correlated modules
- Mitotic Spindle · correlation 0.94
- FA DNA Repair · correlation 0.93
- S-phase DNA Replication · correlation 0.90
- S-phase Replication · correlation 0.86
- OxPhos & RNA Processing · correlation 0.84
- Proliferation RNA Processing · correlation 0.84
- Chromatin Remodeling · correlation 0.82
- DNA Replication · correlation 0.81
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.