Translation-OxPhos housekeeping
Gene co-expression module in Monocytes
| Category | Housekeeping |
|---|---|
| Genes | 0 |
| Annotation certainty | 3 of 5 |
| Annotation consistency | 15 of 41 genes have a known function matching the annotation |
Why this annotation
Highly expressed core module combining two housekeeping arms: - Translation/nascent chain machinery: BTF3, RACK1, PFDN5, EIF3F, SSR2, SSR4, EDF1. - OxPhos subunits: ATP5MC2, ATP5MG, UQCRH, COX4I1, ATP5F1D, TOMM7, SMDT1. This is a general housekeeping translation/mitochondrial program reflecting transcriptional output.
Genes
Most correlated modules
- Translational biosynthesis · correlation 0.92
- Proteostasis-trafficking housekeeping · correlation 0.90
- Mitochondrial-splicing housekeeping · correlation 0.88
- Complex I OxPhos · correlation 0.88
- Mitochondrial complex I · correlation 0.87
- Respiratory chain OxPhos · correlation 0.86
- Translation/biosynthetic capacity · correlation 0.86
- Mixed housekeeping metabolism · correlation 0.86
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.