Leukocyte endothelial adhesion
Gene co-expression module in Monocytes
| Category | Migration & adhesion |
|---|---|
| Genes | 0 |
| Annotation certainty | 2 of 5 |
| Annotation consistency | 7 of 16 genes have a known function matching the annotation |
Why this annotation
PECAM1, SELPLG, ARHGEF1, CCM2, NECTIN1 and ITPKB point to leukocyte–endothelial adhesion and trafficking. TOB1, CCNG2 and RARA add a quiescent, recently extravasated or circulating monocyte state.
Genes
Most correlated modules
- DNA replication/repair · correlation 0.81
- NF-kB Myeloid Activation · correlation 0.81
- Actin-endocytic remodeling · correlation 0.81
- CD16 Monocyte Signature · correlation 0.80
- Patrolling Monocyte Cytoskeleton · correlation 0.79
- Classical monocyte identity · correlation 0.75
- Classical monocyte degranulation · correlation 0.69
- Integrin adhesion signaling · correlation 0.65
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.