Metabolic/trafficking housekeeping
Gene co-expression module in Monocytes
| Category | Housekeeping |
|---|---|
| Genes | 0 |
| Annotation certainty | 1 of 5 |
| Annotation consistency | 11 of 28 genes have a known function matching the annotation |
Why this annotation
Genes cover metabolism (ME2, HK1, DERA), trafficking (CHM, SEC22A, SYNRG, MADD, COMMD1), autophagy (ATG10), MAPK8, ABCC1 and zinc transport (SLC30A9). There is no coherent signalling program and expression is uniform. This is likely part of the same broad housekeeping co-expression axis seen in neighboring modules.
Genes
Most correlated modules
- mTORC1 nutrient sensing · correlation 0.93
- Long-gene housekeeping · correlation 0.92
- Nuclear RNA processing · correlation 0.92
- mRNA processing/export · correlation 0.91
- Long-transcript housekeeping · correlation 0.90
- Transcription/trafficking housekeeping · correlation 0.88
- Chromatin remodeling housekeeping · correlation 0.88
- KZFP/housekeeping transcripts · correlation 0.87
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.