Long-transcript housekeeping
Gene co-expression module in Monocytes
| Category | Housekeeping |
|---|---|
| Genes | 0 |
| Annotation certainty | 2 of 5 |
| Annotation consistency | 12 of 25 genes have a known function matching the annotation |
Why this annotation
Mixes Golgi/autophagy genes (AKAP9, GOLGB1, BCAS3, PIK3C3), RNA processing and decay genes (PNISR, ZFC3H1, LSM14A), and chromatin/DNA repair genes (NCOA6, STAG2, RNF169, TRIM33). All are long, ubiquitously expressed genes. It belongs to the same housekeeping long-transcript axis as its neighbors.
Genes
Most correlated modules
- Ubiquitin ligase housekeeping · correlation 0.97
- Chromatin remodeling housekeeping · correlation 0.94
- Chromatin repression housekeeping · correlation 0.93
- Nuclear RNA processing · correlation 0.93
- Transcriptional coregulators · correlation 0.92
- Cullin-RING ubiquitination · correlation 0.90
- Metabolic/trafficking housekeeping · correlation 0.90
- mTORC1 nutrient sensing · correlation 0.89
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.