Transcription/trafficking housekeeping
Gene co-expression module in Monocytes
| Category | Housekeeping |
|---|---|
| Genes | 0 |
| Annotation certainty | 1 of 5 |
| Annotation consistency | 9 of 15 genes have a known function matching the annotation |
Why this annotation
Genes cover transcription elongation and chromatin regulation (IWS1, CDK8, BAZ1B, NCOR2, GPATCH2), Golgi/vesicle trafficking (USO1, CLINT1, VTA1, GALNT1), peroxisomal AGPS, GCN2 (EIF2AK4) and CBLB. Expression is uniform. Together with its neighbors, this is a nonspecific housekeeping co-expression module.
Genes
Most correlated modules
- Long-gene housekeeping · correlation 0.95
- General cellular maintenance · correlation 0.95
- Generic housekeeping transcripts · correlation 0.94
- mTORC1 nutrient sensing · correlation 0.94
- mRNA processing/export · correlation 0.94
- Nuclear RNA processing · correlation 0.92
- Mitochondrial translation/metabolism · correlation 0.91
- Small GTPase signaling · correlation 0.90
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.