Long-gene nuclear transcripts
Gene co-expression module in Monocytes
| Category | Housekeeping |
|---|---|
| Genes | 0 |
| Annotation certainty | 2 of 5 |
| Annotation consistency | 7 of 24 genes have a known function matching the annotation |
Why this annotation
This is a mixed set of long genes with uniform expression. Members span DNA repair (MSH3, ATM, MCM9), chromatin (SMARCA2, BOD1L1), mRNA decay (DDX6, UPF2), trafficking (STX7, EXOC1, PDCD6IP) and signaling (PRKAA1, MAP3K7, NFATC3). No coherent cell-state program emerges. It belongs to the same nuclear and long-transcript housekeeping cluster as its neighbors.
Genes
Most correlated modules
- Nuclear regulator transcripts · correlation 0.92
- Mitochondrial/ER housekeeping · correlation 0.91
- Chromatin regulator transcripts · correlation 0.90
- Transcription/RNA processing · correlation 0.88
- Chromatin regulator transcripts · correlation 0.87
- Small GTPase signaling · correlation 0.85
- Mixed low-level transcripts · correlation 0.82
- Chromatin regulator transcripts · correlation 0.81
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.