Generic housekeeping
Gene co-expression module in Neutrophils
| Category | Housekeeping |
|---|---|
| Genes | 0 |
| Annotation certainty | 2 of 5 |
| Annotation consistency | 4 of 7 genes have a known function matching the annotation |
Why this annotation
This is a small module of ubiquitously expressed genes: GNAS (G-protein alpha-s), ARPC3 (Arp2/3 complex), ATP5F1E (ATP synthase), BNIP2, WSB1 and FAM200B. There is no coherent neutrophil-specific program, and expression is moderate and uniform. It most likely reflects a general housekeeping or library-complexity axis that correlates with its neighbors.
Genes
Most correlated modules
- Glucocorticoid alarmin response · correlation 0.78
- Mature circulating neutrophil · correlation 0.69
- Mature antimicrobial recognition · correlation 0.65
- Ubiquitin-proteasome system · correlation 0.65
- Rolling & formyl-peptide motility · correlation 0.60
- TLR4/LPS activation · correlation 0.60
- Pro-resolving tissue state · correlation 0.58
- Tissue-activated inflammatory neutrophil · correlation 0.56
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.