Epigenetic Regulation
Gene co-expression module in Plasmacytoid dendritic cells
| Category | Housekeeping |
|---|---|
| Genes | 0 |
| Annotation certainty | 1 of 5 |
| Annotation consistency | 5 of 13 genes have a known function matching the annotation |
Why this annotation
All genes show weak membership and uniform expression with unknown coherence. Gene composition includes: METTL14 (m6A RNA methyltransferase, epitranscriptomic regulation), PAXIP1 (PTIP, chromatin/DNA repair scaffold), ERCC2 (XPD helicase, nucleotide excision repair), DNAJC2 (HSP40 chaperone, ribosome biogenesis), PSPH (phosphoserine phosphatase, serine biosynthesis), CEBPG (C/EBP transcription factor), MTSS1 (metastasis suppressor, actin regulation), SLC39A8 (zinc transporter), PMPCA (mitochondrial processing peptidase). Loosely connected by chromatin/RNA regulation but too heterogeneous for a specific label. Neighbors in the batch are similarly mixed housekeeping modules.
Genes
Most correlated modules
- Mixed Housekeeping · correlation 0.87
- Mixed Housekeeping · correlation 0.83
- TLR Signaling Regulation · correlation 0.81
- Chromatin Regulation · correlation 0.79
- Mixed Housekeeping · correlation 0.74
- CX3CR1 Migration · correlation 0.72
- Low-coherence Background · correlation 0.71
- Cilia & Centrosome · correlation 0.62
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.