ACAA1 — Acetyl-CoA acyltransferase 1
ACAA1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ACAA1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | CD4 Lineage Identity T cell development | AGPAT3, ASCC3, ATF2, KIFAP3, KXD1, NEK7, PARP4, PPM1A +6 more | View in SCUBA |
| Innate lymphoid cells | Transcriptional Regulation DNA regulation & transcription | ATRX, C1orf43, CARHSP1, CHTOP, CTDSP1, CTR9, DRAP1, ELOVL6 +18 more | View in SCUBA |
About the gene
| Synonyms | Lnc-Myd88 |
|---|---|
| Chromosome | 3: 38103129-38137242 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Acyltransferase, Transferase |
| Biological process | Fatty acid metabolism, Lipid metabolism |
Function
Responsible for the thiolytic cleavage of straight chain 3- keto fatty acyl-CoAs (3-oxoacyl-CoAs). Plays an important role in fatty acid peroxisomal beta-oxidation. Catalyzes the cleavage of short, medium, long, and very long straight chain 3- oxoacyl-CoAs
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.