C1ORF43 — Chromosome 1 open reading frame 43
C1ORF43 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
C1ORF43's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | mRNA splicing RNA processing | ANAPC5, C11orf58, DDX46, DNAJC7, HSPA4, LSM14A, LUC7L3, MRPL47 +8 more | View in SCUBA |
| Gamma-delta T cells | RNA Binding/Splicing RNA processing & translation | AIMP1, ATP11B, CCT2, DEDD2, DGKD, ENSA, ENY2, FBXL14 +18 more | |
| Innate lymphoid cells | Transcriptional Regulation DNA regulation & transcription | ACAA1, ATRX, CARHSP1, CHTOP, CTDSP1, CTR9, DRAP1, ELOVL6 +18 more | View in SCUBA |
| Macrophages | Proteasome UPS Housekeeping | ATP6V1D, ATP6V1E1, BAX, COX7A2L, DCUN1D5, DNAJC15, DNAJC8, ENY2 +28 more | View in SCUBA |
| Smooth muscle cells | Basal Metabolic Housekeeping Housekeeping | ARPC2, C11orf58, C4orf3, CNBP, COX17, GUK1, HNRNPDL, HNRNPH2 +6 more | View in SCUBA |
About the gene
| Synonyms | DKFZp586G1722, NICE-3 |
|---|---|
| Chromosome | 1: 154206696-154220637 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
Function
General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.