CA12 — Carbonic anhydrase 12
CA12 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CA12's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Chemokine-secreting Fibroblasts Inflammatory | CCBE1, CHI3L2, CPXM2, CXCL13, CXCL5, GAS1, GPM6B, IGFBP2 +10 more | View in SCUBA |
| Goblet cells | Goblet Cell Identity Mucus production & secretion | AGR3, CD9, FAM162A, IL1R2, LGALS4, NDUFA1, SCP2, TMEM141 +1 more | View in SCUBA |
About the gene
| Synonyms | HsT18816 |
|---|---|
| Chromosome | 15: 63321378-63381846 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins |
| Molecular function | Lyase |
Function
Reversible hydration of carbon dioxide
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.