COLQ — Collagen like tail subunit of asymmetric acetylcholinesterase
COLQ belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
COLQ's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Cytokine signaling Immune regulation | ABCB1, ARHGEF40, AUTS2, DSE, ERN1, GPR65, IFI44, IFNGR1 +12 more | View in SCUBA |
| Gamma-delta T cells | γδT17 Effector Inflammation | AQP3, CCR6, CEBPD, CTSA, CTSH, EDEM2, GCHFR, IL23R +10 more | |
| Mucosal-associated invariant T cell | IL-18 Innate Activation Inflammation | ADAM10, IL18RAP, KIF5C, ME1, MYBL1, NEO1, P2RY14, PARP8 +3 more | |
| Natural Killer cells | NK Cell Identity Differentiation | APBA2, APMAP, ETS1, FCMR, FKBP11, GSAP, ICAM2, MRPL10 +2 more | View in SCUBA |
About the gene
| Synonyms | EAD |
|---|---|
| Chromosome | 3: 15450133-15521751 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins |
| Biological process | Neurotransmitter degradation |
Function
Anchors the catalytic subunits of asymmetric AChE to the synaptic basal lamina
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.