BCL9L — BCL9 like
BCL9L belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BCL9L's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Naive T cell quiescence T cell maturation | ADAP1, ARL4C, BMAL1, CALM1, CAMK1D, CD44, CD5, CD6 +10 more | |
| Mucosal-associated invariant T cell | PI3K-Calcineurin Signaling TCR Signaling | ACLY, CABIN1, CDK11A, LATS2, NBPF19, NUP210, PIK3CD, POM121C +2 more |
About the gene
| Synonyms | B9L, Bcl9-2, DLNB11 |
|---|---|
| Chromosome | 11: 118893875-118925926 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Predicted intracellular proteins |
| Molecular function | Activator |
| Biological process | Transcription, Transcription regulation |
Function
Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1 (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.