POM121C — POM121 transmembrane nucleoporin C
POM121C belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
POM121C's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | ER Protein Translocation Protein processing & ER | ATG2A, BEST1, CLSTN1, CTDSP2, GALC, GSE1, HAPSTR1, HOOK2 +12 more | |
| Macrophages | Transcriptional Regulation Housekeeping | AATF, ABHD5, ARID3B, DCP1A, GGNBP2, MIA2, MSI2, NR2C2 +18 more | View in SCUBA |
| Mucosal-associated invariant T cell | PI3K-Calcineurin Signaling TCR Signaling | ACLY, BCL9L, CABIN1, CDK11A, LATS2, NBPF19, NUP210, PIK3CD +2 more |
About the gene
| Chromosome | 7: 75416786-75486299 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins, Transporters |
| Biological process | mRNA transport, Protein transport, Translocation, Transport |
Function
Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.