DDC — Dopa decarboxylase
DDC belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DDC's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Carbohydrate Digestion/Detox Nutrient metabolism | CBR1, CMBL, GSTA1, HADHB, KBTBD11, MAOA, PEBP1, SI +1 more | View in SCUBA |
About the gene
| Synonyms | AADC |
|---|---|
| Chromosome | 7: 50458436-50565405 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Decarboxylase, Lyase |
| Biological process | Catecholamine biosynthesis |
Function
Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine and L-5-hydroxytryptophan to serotonin
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.