SI — Sucrase-isomaltase
SI belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SI's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Carbohydrate Digestion/Detox Nutrient metabolism | CBR1, CMBL, DDC, GSTA1, HADHB, KBTBD11, MAOA, PEBP1 +1 more | View in SCUBA |
| Goblet cells | Epithelial Maturation Epithelial development | AMN, BAG1, CDC42EP5, CST3, KRT10, NTRK2, NXPE4, PHGR1 +2 more | View in SCUBA |
About the gene
| Chromosome | 3: 164978898-165078496 |
|---|---|
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins |
| Molecular function | Glycosidase, Hydrolase, Multifunctional enzyme |
Function
Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.