DDX47 — DEAD-box helicase 47
DDX47 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DDX47's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Naive T cell quiescence T cell maturation | ADAP1, ARL4C, BCL9L, BMAL1, CALM1, CAMK1D, CD44, CD5 +10 more | |
| Mucosal-associated invariant T cell | TGF-beta Response Immune regulation | ABCA1, ARL4C, ARRDC2, CD48, DNLZ, ERGIC1, FMNL1, HYPK +21 more |
About the gene
| Synonyms | DKFZp564O176, FLJ30012, HQ0256, RRP3 |
|---|---|
| Chromosome | 12: 12813316-12829981 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Helicase, Hydrolase, RNA-binding |
| Biological process | Apoptosis, mRNA processing, mRNA splicing, rRNA processing |
Function
Required for efficient ribosome biogenesis (By similarity). May have a role in mRNA splicing. Involved in apoptosis.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.