DYNLL2 — Dynein light chain LC8-type 2
DYNLL2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DYNLL2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Transcriptional regulation DNA/chromatin regulation | CCNH, CWC25, EIF2A, GOLGB1, IVNS1ABP, JMJD1C, KRR1, LPIN2 +8 more | View in SCUBA |
| Gamma-delta T cells | Anabolic Activation Response Housekeeping | ABHD5, ATF4, ATP6V0C, ATP6V1G1, BCL7B, BUD31, CALM2, CHRAC1 +26 more | |
| Mucosal-associated invariant T cell | mRNA Decay Program RNA processing & translation | ATP6V0C, BCL7B, BTG1, BTG3, CCDC59, DDIT4, DUSP2, EXOSC6 +13 more |
About the gene
| Synonyms | Dlc2, DNCL1B, MGC17810, RSPH22 |
|---|---|
| Chromosome | 17: 58083419-58095542 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Motor protein |
| Biological process | Transport |
Function
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.