BCL7B — BAF chromatin remodeling complex subunit BCL7B
BCL7B belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BCL7B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Anabolic Activation Response Housekeeping | ABHD5, ATF4, ATP6V0C, ATP6V1G1, BUD31, CALM2, CHRAC1, DYNLL2 +26 more | |
| Macrophages | ER Protein Translocation Vesicular traficking | ACADVL, ARRB2, BORCS7, DDRGK1, DEF8, DNAJB12, DVL3, ELOVL1 +22 more | View in SCUBA |
| Mucosal-associated invariant T cell | mRNA Decay Program RNA processing & translation | ATP6V0C, BTG1, BTG3, CCDC59, DDIT4, DUSP2, DYNLL2, EXOSC6 +13 more |
About the gene
| Synonyms | SMARCJ2 |
|---|---|
| Chromosome | 7: 73536356-73557690 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Biological process | Apoptosis, Differentiation, Wnt signaling pathway |
Function
Positive regulator of apoptosis. Plays a role in the Wnt signaling pathway, negatively regulating the expression of Wnt signaling components CTNNB1 and HMGA1. Involved in cell cycle progression, maintenance of the nuclear structure and stem cell differentiation. May play a role in lung tumor development or progression (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.