FGF7 — Fibroblast growth factor 7
FGF7 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FGF7's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | OSM Cytokine Response Inflammatory | ARID5B, ELK3, OSMR, PDE4B, PTGER1, RNF145, UFM1 | View in SCUBA |
| Smooth muscle cells | Pericyte Vasoregulatory Identity Contractility | ABCC9, ADRA2C, CCDC80, CFH, FEZ2, KCNJ8, PCSK1N, PROS1 +6 more | View in SCUBA |
About the gene
| Synonyms | KGF |
|---|---|
| Chromosome | 15: 49423237-49488775 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins |
| Molecular function | Growth factor, Heparin-binding, Mitogen |
Function
Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.