ADRA2C — Adrenoceptor alpha 2C
ADRA2C belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ADRA2C's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Inflammatory ECM Remodeling ECM remodeling | ABI3BP, ANXA3, CGNL1, CLIC3, ELN, FBLN2, FGF18, GUCY1A1 +5 more | View in SCUBA |
| Smooth muscle cells | Pericyte Vasoregulatory Identity Contractility | ABCC9, CCDC80, CFH, FEZ2, FGF7, KCNJ8, PCSK1N, PROS1 +6 more | View in SCUBA |
About the gene
| Synonyms | ADRA2L2, ADRA2RL2, ADRARL2 |
|---|---|
| Chromosome | 4: 3766348-3768526 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins |
| Molecular function | G-protein coupled receptor, Receptor, Transducer |
Function
Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.