PI15 — Peptidase inhibitor 15
PI15 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PI15's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Chemokine-secreting Fibroblasts Inflammatory | CA12, CCBE1, CHI3L2, CPXM2, CXCL13, CXCL5, GAS1, GPM6B +10 more | View in SCUBA |
| Smooth muscle cells | ER-Golgi Secretory Pathway Protein processing & ER | BZW1, CCT3, COL15A1, GPC6, IFT57, KDELR2, LRPAP1, NFATC4 +4 more | View in SCUBA |
About the gene
| Synonyms | P25TI |
|---|---|
| Chromosome | 8: 74824534-74855029 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Predicted secreted proteins |
| Molecular function | Developmental protein, Protease inhibitor |
Function
Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.