LRPAP1 — LDL receptor related protein associated protein 1
LRPAP1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LRPAP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | TGF-beta Signaling Immune regulation | ABCF1, ABHD12, ACAP2, ADIPOR2, CBX6, ENPP4, FBXO9, GSAP +18 more | |
| Lymphatic endothelial | Caveolae Cytoskeletal Cytoskeletal | CALM1, CAVIN1, CRIP2, CTSZ, DYNLL1, EPHX1, GSTK1, HOXD8 +7 more | View in SCUBA |
| Macrophages | ERAD Proteasome Housekeeping | ADRM1, EIF6, EMC6, GLRX3, GNPTG, MAP2K2, MED8, MIEN1 +16 more | View in SCUBA |
| Smooth muscle cells | ER-Golgi Secretory Pathway Protein processing & ER | BZW1, CCT3, COL15A1, GPC6, IFT57, KDELR2, NFATC4, PAM +4 more | View in SCUBA |
About the gene
| Synonyms | A2MRAP, HBP44, RAP |
|---|---|
| Chromosome | 4: 3503612-3532446 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Molecular function | Heparin-binding |
Function
Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.