PMS1 — PMS1 homolog 1, mismatch repair system component
PMS1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PMS1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | SR Kinase & RNA RNA processing & translation | ADHFE1, ATF2, BCAP31, C4orf3, CCPG1, CHKB, CLK2, EFR3A +17 more | |
| Mucosal-associated invariant T cell | Chemokine Receptor Migration migration & adhesion | CCR1, CCR2, CCR5, CD47, FAM78A, KRIT1, LUC7L3, MTG1 +6 more |
About the gene
| Synonyms | MLH2, PMSL1 |
|---|---|
| Chromosome | 2: 189784085-189877629 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | DNA-binding |
| Biological process | DNA damage, DNA repair |
Function
Probably involved in the repair of mismatches in DNA
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.