SCUBA

LUC7L3 — LUC7 like 3 pre-mRNA splicing factor

LUC7L3 belongs to a gene co-expression module in 11 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

LUC7L3's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsmRNA splicing
RNA processing
ANKRD11, ARGLU1, CYBC1, PLCG2, PNN, SON, SRRM2, TCIRG1 +1 moreView in SCUBA
CD4⁺ T cellsmRNA splicing
RNA processing
ANAPC5, C11orf58, C1orf43, DDX46, DNAJC7, HSPA4, LSM14A, MRPL47 +8 moreView in SCUBA
Gamma-delta T cellsmRNA Splicing Regulation
RNA processing & translation
CNOT11, CNOT4, CPNE1, CREB1, GATAD1, GTF2A1, LMBRD1, METTL23 +10 more
Glial cellsRNA Splicing Regulation
RNA processing & translation
ARGLU1, COL16A1, DDX17, DST, N4BP2L2, NRBP2, PNISR, SYNE2 +2 moreView in SCUBA
Goblet cellsRNA Splicing
RNA processing & translation
ARGLU1, C6orf62, EPHB3, FUS, HNRNPH1, HNRNPU, NOP53View in SCUBA
Innate lymphoid cellsGolgi RNA Processing
RNA processing & translation
ANKRD12, ATM, DDX17, GCC2, GOLGA4, MIER1, MLEC, MYCBP2 +11 moreView in SCUBA
Lymphatic endothelialPre-mRNA Splicing
RNA processing & translation
ARGLU1, ATRX, BPTF, DDX17, DST, N4BP2L2, NKTR, PNISR +6 moreView in SCUBA
MacrophagesPre-mRNA Splicing
Housekeeping
AAK1, ANKRD12, ANKRD13D, ARGLU1, BRD2, C3orf62, CREBZF, DMTF1 +20 moreView in SCUBA
Mucosal-associated invariant T cellChemokine Receptor Migration
migration & adhesion
CCR1, CCR2, CCR5, CD47, FAM78A, KRIT1, MTG1, PHF14 +6 more
Natural Killer cellsmRNA Splicing
RNA processing & translation
CHMP4A, DDX17, FAM107B, FKBP2, GOLGB1, HNRNPH1, PNN, RSRC2 +1 moreView in SCUBA
NeutrophilsmRNA Splicing Processing
Housekeeping
ABCA13, ATP2A3, EMB, FBXO9, NKTR, OGT, PAXBP1, PNN +8 more

About the gene

SynonymsCRA, CREAP-1, CROP, FLJ11063, hLuc7A, LUC7A, OA48-18
Chromosome17: 50719565-50756219
Predicted locationIntracellular
Essential geneYes
Protein classEssential proteins, Plasma proteins, Predicted intracellular proteins
Molecular functionDNA-binding
Biological processmRNA processing, mRNA splicing

Function

Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.