CHKB — Choline kinase beta
CHKB belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CHKB's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | SR Kinase & RNA RNA processing & translation | ADHFE1, ATF2, BCAP31, C4orf3, CCPG1, CLK2, EFR3A, FASTK +17 more | |
| Innate lymphoid cells | ILC3 identity Differentiation | ABCC1, BCL6, CCND3, CELF2, DNAAF2, ENSG00000285976, EREG, FKBP5 +31 more | View in SCUBA |
| Mucosal-associated invariant T cell | T cell Identity T cell maturation | ARPC1B, BLOC1S1, C4orf3, CD3D, CPNE1, DDX39B, HMGN3, MARCHF9 +9 more |
About the gene
| Synonyms | CHETK, CHKL |
|---|---|
| Chromosome | 22: 50578959-50601455 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Kinase, Transferase |
| Biological process | Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism |
Function
Has a key role in phospholipid metabolism, and catalyzes the first step of phosphatidylethanolamine and phosphatidylcholine biosynthesis.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.