POP7 — POP7 homolog, ribonuclease P/MRP subunit
POP7 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
POP7's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | RNA Processing RNA processing | ANP32A, CCDC167, CDK4, CENPX, CYC1, FDPS, GGCT, LSM3 +14 more | View in SCUBA |
| Gamma-delta T cells | Chromatin Architecture DNA/chromatin regulation | CBFB, CCDC137, CTCF, DCAF15, GMCL1, HNRNPUL2, HP1BP3, KDM4A +9 more |
About the gene
| Synonyms | RPP2, RPP20 |
|---|---|
| Chromosome | 7: 100706121-100707486 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Molecular function | RNA-binding |
| Biological process | rRNA processing, tRNA processing |
Function
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.