PRUNE2 — Prune homolog 2 with BCH domain
PRUNE2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PRUNE2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | ICC contractility Gut motility | BEX1, BTC, DES, HACD1, HSPB7, IL17B, KCNMA1, LDB3 +7 more | View in SCUBA |
| Goblet cells | Inflammatory Goblet Remodeling Stress | C2CD4A, CLCA1, COL16A1, FMOD, GALNT8, GPX2, IFITM2, KCNE3 +3 more | View in SCUBA |
| Smooth muscle cells | SMC Contractile Signaling Contractility | ACAA2, BOC, CELF2, PLEKHO1, RGS2, SCARA3, SDC3 | View in SCUBA |
About the gene
| Synonyms | A214N16.3, bA214N16.3, BMCC1, BNIPXL, C9orf65, KIAA0367 |
|---|---|
| Chromosome | 9: 76611376-76906114 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
| Biological process | Apoptosis |
Function
May play an important role in regulating differentiation, survival and aggressiveness of the tumor cells
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.