SCML1 — Scm polycomb group protein like 1
SCML1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SCML1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Naive T cell T cell development | AIF1, AK5, APBA2, BEND5, BEX2, C1orf162, CBR3, CYSLTR1 +21 more | View in SCUBA |
| Macrophages | Autophagy Vesicle Trafficking Lysosomal & pahgocytosis | ADNP2, AGO2, AP1G1, ARFGAP3, ATG2A, BANP, CHD1, CHD2 +26 more | View in SCUBA |
About the gene
| Chromosome | X: 17737449-17754988 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Repressor |
| Biological process | Transcription, Transcription regulation |
Function
Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. May be involved in spermatogenesis during sexual maturation (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.