SLAMF8 — SLAM family member 8
SLAMF8 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLAMF8's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Activated Effector ISG Anti-viral | GOLGA7B, KIF5C, KIT, MAP2K6, MVB12B, NMUR1, PLCG1, PLOD3 +8 more | View in SCUBA |
| Fibroblasts | Chemokine-secreting Fibroblasts Inflammatory | CA12, CCBE1, CHI3L2, CPXM2, CXCL13, CXCL5, GAS1, GPM6B +10 more | View in SCUBA |
| Macrophages | Oxidative Metabolic Program Mitochondrial & OxPhos | ACADM, CA2, CALM3, CAPG, COQ2, CSRP1, CSTB, DENND2D +29 more | View in SCUBA |
About the gene
| Synonyms | BLAME, CD353, SBBI42 |
|---|---|
| Chromosome | 1: 159826811-159837492 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | CD markers, Predicted membrane proteins |
Function
May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.