SLC15A1 — Solute carrier family 15 member 1
SLC15A1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC15A1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Amino acid absorption Absorption | ACE2, C1orf115, CREB3L3, FAM3C, SELENOP, SLC6A19, TOR1AIP2 | View in SCUBA |
About the gene
| Synonyms | HPECT1, HPEPT1, PEPT1 |
|---|---|
| Chromosome | 13: 98683801-98752672 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Metabolic proteins, Predicted membrane proteins, Transporters |
| Biological process | Peptide transport, Protein transport, Symport, Transport |
Function
Electrogenic proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Transports neutral and monovalently charged peptides with a proton to peptide stoichiometry of 1:1 or 2:1 (By similarity). Primarily responsible for the absorption of dietary di- and tripeptides from the small intestinal lumen (By similarity). Mediates transepithelial transport of muramyl and N-formylated bacterial dipeptides contributing to recognition of pathogenic bacteria by the mucosal immune system.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.