FAM3C — FAM3 metabolism regulating signaling molecule C
FAM3C belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FAM3C's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | MHC-II antigen presentation B cell maturation | CD53, CD81, CYTH1, DAPP1, DNAJC10, FCRLA, GPR18, HLA-DMA +11 more | View in SCUBA |
| CD8⁺ T cells | Tissue residence Gut residence | AFAP1L2, HTRA1, KIR2DL4, KRT81, KRT86, NBL1, PLPP1, PTPN6 +1 more | View in SCUBA |
| Enterocytes | Amino acid absorption Absorption | ACE2, C1orf115, CREB3L3, SELENOP, SLC15A1, SLC6A19, TOR1AIP2 | View in SCUBA |
| Gamma-delta T cells | Hypoxia Tissue Adaptation Tissue residence | ABCB1, ADAMTS17, ANKRD28, CCRL2, EPAS1, KLHL6, LDLRAD4, PHTF1 +10 more | |
| Natural Killer cells | Gut-Homing NK Gut residency | CCR9, GRAMD2B, OXNAD1, PLPP1, PRKAR2B, SMIM3, SNX9, TRAT1 | View in SCUBA |
About the gene
| Synonyms | GS3876, ILEI |
|---|---|
| Chromosome | 7: 121348878-121396364 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins |
| Molecular function | Developmental protein |
Function
May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.