SCUBA

SELENOP — Selenoprotein P

SELENOP belongs to a gene co-expression module in 9 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

SELENOP's module in each cell type

Cell typeModuleShares the module with
EndothelialVenous EC Identity
Endothelial cell development
CAVIN2, CEACAM1, CYBA, DNMBP, EFCC1, EPHX1, GMFG, HID1 +7 moreView in SCUBA
EnterocytesAmino acid absorption
Absorption
ACE2, C1orf115, CREB3L3, FAM3C, SLC15A1, SLC6A19, TOR1AIP2View in SCUBA
FibroblastsQuiescent Stromal Identity
Developmental
ADH1B, CXCL12, FXYD1, GSN, GSTM5, METTL7A, NFIA, PLAC9 +1 moreView in SCUBA
Glial cellsNeuroprotective Secretory
Neroprotection
ANGPTL7, APCDD1, IGFBP6, LRRTM1, PDLIM2, PRELP, TTR, TXNIP +1 moreView in SCUBA
Goblet cellsInflammatory goblet response
Immune function
ANXA1, B4GALT1, CAPN8, CEACAM6, DST, KRT20, LYPD8, MUC13 +8 moreView in SCUBA
Hematopoietic progenitor cellsT-cell Progenitor
Lymphcyte development
DSC2, GATA3, HOXB5, LAG3, MDK, OPTN, PTMS, SKAP1 +2 more
Lymphatic endothelialOxidative Stress Protection
Stress
ALDH2, ANAPC16, BCL7C, CAVIN2, CCL21, CD320, CRACR2B, FXYD6 +10 moreView in SCUBA
MacrophagesAntimicrobial Oxidative Defense
Antibacterial
ADAMDEC1, ALDOA, APOL3, CALHM6, CLEC10A, COX16, CPVL, DEFA5 +30 moreView in SCUBA
MonocytesTissue-Resident Macrophage
Tissue adaptation
DAB2, ETV5, FOLR2, FRMD4A, GPNMB, ITGB5, LGMN, LILRB5 +7 moreView in SCUBA

About the gene

SynonymsSELP, SeP, SEPP, SEPP1
Chromosome5: 42799880-42887392
Predicted locationMembrane, Secreted
Essential geneNo
Protein classPlasma proteins, Predicted membrane proteins, Predicted secreted proteins

Function

Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.