TOR1AIP2 — Torsin 1A interacting protein 2
TOR1AIP2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TOR1AIP2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | IL10/cytokine signaling Immune regulation | CASK, CCDC141, FOXN3, IL10RA, IL7, SLC12A6, STAMBPL1, TMEM154 +4 more | View in SCUBA |
| Enterocytes | Amino acid absorption Absorption | ACE2, C1orf115, CREB3L3, FAM3C, SELENOP, SLC15A1, SLC6A19 | View in SCUBA |
| Macrophages | Ubiquitin-ERAD Proteostasis Housekeeping | GSPT1, HSPA9, ITCH, MAPK1IP1L, PANK3, PJA2, SEL1L, USP39 +1 more | View in SCUBA |
About the gene
| Synonyms | IFRG15, LULL1, NET9 |
|---|---|
| Chromosome | 1: 179839967-179877803 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
Function
Required for endoplasmic reticulum integrity. Regulates the distribution of TOR1A between the endoplasmic reticulum and the nuclear envelope as well as induces TOR1A, TOR1B and TOR3A ATPase activity.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.