TIMMDC1 — Translocase of inner mitochondrial membrane domain containing 1
TIMMDC1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TIMMDC1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Oxidative phosphorylation Mitochondrial & OxPhos | ACADVL, CHMP1A, COX14, EIF2AK1, EML2, ETFA, GPR108, NDUFA8 +12 more | View in SCUBA |
| Endothelial | TRAIL-mediated Apoptosis Stress | CLDN15, ELOVL7, EVA1C, FGD4, ISCU, LMCD1, SELENOM, TMEM273 +2 more | View in SCUBA |
| Gamma-delta T cells | mRNA Splicing Regulation RNA processing & translation | CNOT11, CNOT4, CPNE1, CREB1, GATAD1, GTF2A1, LMBRD1, LUC7L3 +10 more |
About the gene
| Synonyms | C3orf1, FLJ22597 |
|---|---|
| Chromosome | 3: 119498547-119525090 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Chaperone |
Function
Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Participates in constructing the membrane arm of complex I
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.