SCUBA

SELENOM — Selenoprotein M

SELENOM belongs to a gene co-expression module in 9 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

SELENOM's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsB-cell Maturation
B cell maturation		ANK3, ANTXR2, CD24, COL4A3, COL4A4, CSGALNACT1, ITM2C, PDCD4 +3 moreView in SCUBA
EndothelialTRAIL-mediated Apoptosis
Stress		CLDN15, ELOVL7, EVA1C, FGD4, ISCU, LMCD1, TIMMDC1, TMEM273 +2 moreView in SCUBA
Gamma-delta T cellsRedox Stress Response
Stress		BEX2, BEX4, CITED4, EEF1A1, FMNL3, FTL, GRINA, LTBP3 +5 more
Glial cellsProteasomal Proteostasis
Protein processing & ER		CD63, CLIC1, COX7A2, ELOB, MYL12B, PDIA6, PSMA7, PSMB1 +3 moreView in SCUBA
Goblet cellsGoblet Secretory Identity
Mucus production & secretion		ARFIP2, C12orf57, CREB3L4, FRZB, GMDS, HID1, HSPA2, KCNMA1 +8 moreView in SCUBA
Innate lymphoid cellsER Stress UPR
Stress		ERN1, HLA-DPA1, HLA-DRA, IL7R, NEO1, PRKCAView in SCUBA
Lymphatic endothelialGenotoxic Innate Inflammation
Inflammation		CSF2, CSF3, E2F7, GBP2, NBN, PLA1A, RIPK2, SQOR +1 moreView in SCUBA
PericytesComplement Regulatory Pericyte
Inflammatory		ACTN1, CD63, CFH, IGFBP7, LGALS1, MGP, SERPING1View in SCUBA
Smooth muscle cellsAmbient High-Expressors
Technical artifact		ATP5MD, ATP5MPL, C19orf70, H2AFZ, H3F3A, H3F3B, MALAT1, MTRNR2L12 +2 moreView in SCUBA

About the gene

SynonymsSELM, SEPM
Chromosome22: 31104772-31120069
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins

Function

May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.