ZPR1 — ZPR1 zinc finger
ZPR1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ZPR1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Mucosal-associated invariant T cell | Transcription Factor Activity DNA/chromatin regulation | AKAP17A, BTAF1, HNRNPH1, HSPA9, IKZF5, LCOR, NDEL1, POLR2M +3 more |
About the gene
| Synonyms | ZNF259 |
|---|---|
| Chromosome | 11: 116773799-116788039 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Disease related genes, Essential proteins, Predicted intracellular proteins |
| Biological process | Differentiation, mRNA processing, mRNA splicing |
Function
Acts as a signaling molecule that communicates proliferative growth signals from the cytoplasm to the nucleus. It is involved in the positive regulation of cell cycle progression. Plays a role for the localization and accumulation of the survival motor neuron protein SMN1 in sub-nuclear bodies, including gems and Cajal bodies. Induces neuron differentiation and stimulates axonal growth and formation of growth cone in spinal cord motor neurons. Plays a role in the splicing of cellular pre-mRNAs. May be involved in H(2)O(2)-induced neuronal cell death.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.