ATP Synthase OXPHOS
Gene co-expression module in Enterocytes
| Category | Mitochondrial & OxPhos |
|---|---|
| Genes | 8 |
| Annotation certainty | 5 of 5 |
| Annotation consistency | 6 of 8 genes have a known function matching the annotation |
Why this annotation
Dominated by ATP synthase subunits (ATP5MF, ATP5F1B, ATP5MK, ATP5F1A) and complex IV subunits (COX4I1, COX7A2). EIF3K and DBI are highly expressed co-varying passengers. This is an ATP synthase-centered OXPHOS module that complements M14 and M70.
Genes
ATP5F1A, ATP5F1B, ATP5MF, ATP5MK, COX4I1, COX7A2, DBI, EIF3K
Most correlated modules
- Electron Transport Chain · correlation 0.95
- Respiratory Chain OXPHOS · correlation 0.94
- Respiratory Chain Subunits · correlation 0.93
- Mitochondrial Chaperonin · correlation 0.91
- Oxidative Phosphorylation · correlation 0.90
- Abundant Transcript Baseline · correlation 0.88
- Translation Elongation · correlation 0.85
- Mitochondrial Energy Metabolism · correlation 0.77
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.