Electron Transport Chain
Gene co-expression module in Enterocytes
| Category | Mitochondrial & OxPhos |
|---|---|
| Genes | 15 |
| Annotation certainty | 5 of 5 |
| Annotation consistency | 15 of 15 genes have a known function matching the annotation |
Why this annotation
Every gene is an electron transport chain subunit, spanning complex IV (COX5B, COX7C, COX6B1, COX8A, COX7B), complex III (UQCR10, UQCR11), complex I (NDUFB2/3/8, NDUFAB1) and ATP synthase (ATP5MJ, ATP5MG, ATP5PO, ATP5PD). This is the purest OXPHOS module in the batch and anchors the neighborhood with M14 and M72.
Genes
ATP5MG, ATP5MJ, ATP5PD, ATP5PO, COX5B, COX6B1, COX7B, COX7C, COX8A, NDUFAB1, NDUFB2, NDUFB3, NDUFB8, UQCR10, UQCR11
Most correlated modules
- Respiratory Chain Subunits · correlation 0.96
- Respiratory Chain OXPHOS · correlation 0.95
- ATP Synthase OXPHOS · correlation 0.95
- Oxidative Phosphorylation · correlation 0.93
- Abundant Transcript Baseline · correlation 0.92
- Mitochondrial Chaperonin · correlation 0.86
- Translation Elongation · correlation 0.85
- Mitochondrial Energy Metabolism · correlation 0.75
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.